Oecd guidelines for dermal toxicity studies

oecd guidelines section 4
acute dermal irritation study
dermal toxicity studies ppt
oecd 402 acute dermal toxicity
oecd 410oecd 411
dermal toxicity studies guidelines
oecd 404

9 Oct 2017 OECD Guidelines for the Testing of Chemicals, Section 4 hazard likely to arise from short-term exposure to a test chemical by dermal route. OECD Guidelines for the Testing of Chemicals: Section 4: Health Effects. Test No. 401: Acute Oral Toxicity OECD Guidelines for the Testing of Chemicals.However, details of the dermal toxicity of M. citrifolia are still undiscovered. Cooperation and Development (OECD) guidelines, toxicological studies. This Test Guideline is intended primarily for use with rodents (rat, rabbit or guinea 402: Acute Dermal Toxicity, OECD Guidelines for the Testing of Chemicals, The OECD Guidelines for the Testing of Chemicals is a collection of about 150 of the most relevant internationally agreed testing methods used by government, OECD Guidelines for the Testing of Chemicals are a set of internationally accepted 213, Honeybees, Acute Oral Toxicity Test. 214, Honeybees, Acute Contact Test No. 410: Repeated Dose Dermal Toxicity: 21/28-day Study. At least 10 animals (5 female and 5 male) with healthy skin should be used at each dose level (at least three). The highest dose level should result in toxic effects but not produce an incidence of fatalities. 14 May 2004 1. OECD Guidelines for the Testing of Chemicals are periodically reviewed in the light of scientific progress and animal welfare considerations. The original acute Dermal Toxicity Guideline TG 402 (1) was adopted in 1987. Traditional methods for assessing acute toxicity use death of animals as the sole endpoint. 24 Apr 2002 Existing human data, e.g. clinical or occupational studies and case reports, and/or animal test data, e.g. from single or repeated dermal exposure 9/13 Page 10 404 OECD/OCDE toxicity studies, should be considered first, because they provide information directly related to effects on the skin.