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Leukotrienes are a family of eicosanoid inflammatory mediators produced in leukocytes by the oxidation of arachidonic acid (AA) and the essential fatty acid eicosapentaenoic acid (EPA) by the enzyme arachidonate 5-lipoxygenase.. Leukotrienes use lipid signaling to convey information to either the cell producing them (autocrine signaling) or neighboring cells (paracrine signaling) in order to ... Unit 1 : The basics of geography. Essays Biographical And Critical The Count of Monte Christo Community Organization for Urban Social Change Det fantastiske barn Niahs Pride (Pryde Ranch Shifters Book 2) F. Marks, G. Fürstenberger (Eds.) Prostaglandins, Leukotrienes, and Other Eicosanoids From Biogenesis to Clinical Application Eicosanoids - derivatives of polyunsaturated fatty acids which are primarily formed along oxidative pathways - constitute one of the most abundant and prominent family of signaling compounds which play a key role in intracellular communication. 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Figure-1- showing the structure of Arachidonic acid