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Multiple sclerosis (MS) historically has been considered a disease of White Matter (WM). 2,3 The classic hallmark of relapsing-remitting MS is the presence of focal demyelinating lesions in WM tissue. 1,4 WM atrophy also has been observed in patients with relapsing forms of MS. 1,5 Consequently, research in MS generally focused on WM pathology for many years. 6 HERE TO HELP. Regional Societies offer a wide variety of support and services for people with MS, families, employers and carers affected by the condition. Know It All! Grades 6-8 Math (K-12 Study Aids) From the Darkness (Blackwood Vampires) Nothingness BEST! Employment Issues And Multiple Sclerosis Rar. The Canadians: Biographies Of A Nation (Volume II) Multiple sclerosis is an autoimmune disease in which the protective myelin sheath of the nerves is damaged, affecting the transmission of messages to and from brain and spinal cord. 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