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Snow's 1849 recommendation that water be "filtered and boiled before it is used" is one of the first practical applications of germ theory in the area of public health and is the antecedent to the modern boil-water advisory.. In 1855 he published a second edition of his article, documenting his more elaborate investigation of the effect of the water supply in the Soho, London epidemic of 1854. Images de Platon et lectures de ses euvres Infection is the invasion of an organism's body tissues by disease-causing agents, their multiplication, and the reaction of host tissues to the infectious agents and the toxins they produce. Infectious disease, also known as transmissible disease or communicable disease, is illness resulting from an infection.. Infections are caused by infectious agents including viruses, viroids, prions ... 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