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Cisplatin (CAS no. 15663-27-1, MF-Cl
2 H 6 N
2 Pt; NCF-119875), cisplatinum, also called cis-diamminedichloroplatinum(II), is a metallic (
platinum)
coordination compound with a square planar geometry (The chemical book database, 2014).It is a white or deep yellow to yellow–orange crystalline powder at room temperature. It is slightly soluble in water and soluble in ...
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Platinum Amine Complexes as Chemotherapeutic Agents. Since the serendipitous discovery of the antitumor properties of cisplatin (cis-(diamminodichloro)
platinum(II), cis-Pt(Cl
2 (NH 3)
2, Figure 1) by Rosenberg et al. [17, 18] and its introduction to oncology, bioinorganic
compounds have gained an increasing interest in the design of both therapeutic and diagnostic agents [21, 38, 49, 98]. BEST Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 PDF
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Break a leg, darlings Good Husband Material (Hometown Heartbreakers) Porsche 914/914/6 Workshop Manual The Taming of the Dudebro The development of resistance to
platinum-based
chemotherapy is a major clinical challenge
in cancer treatment, since the cellular response which confers resistance to carboplatin is multifactorial and poorly understood (Wernyj, Morin, 2004; Shahzad, Berestein, Sood, 2009).It has been observed that the intracellular mechanisms by which cells become resistant to carboplatin include increased ... Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 txt download
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Jack Russell Terriers For Dummies The Art of Choosing: Working Through Daily Decisions and Discerning... Probably the oldest worked specimen of
platinum is that from an ancient Egyptian casket of the 7 th century BC, unearthed at Thebes and dedicated to Queen Shapenapit. Otherwise this
metal was unknown in Europe and Asia for the next two millennia, although on the Pacific coast of South America, there were people able to work
platinum, as shown by burial goods dating back 2000 years.
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Evaluation of Human Work, 3rd Edition Platinum-based antineoplastic drugs (informally called platins) are chemotherapeutic agents used to treat
cancer.They are
coordination complexes of
platinum.These drugs are used to treat almost half of people receiving
chemotherapy for
cancer. In this form of
chemotherapy, popular drugs include cisplatin, oxaliplatin, and carboplatin, but several have been proposed or are under development.
Youthful writings ebook Platinum and Other Metal Coordination Compounds in Cancer Chemotherapy 2 pdf download Characteristics Physical properties. As a
metal,
titanium is recognized for its high strength-to-weight ratio. It is a strong
metal with low density that is quite ductile (especially in an oxygen-free environment), lustrous, and metallic-white in color. The relatively high melting point (more than 1,650 °C or 3,000 °F) makes it useful as a refractory
metal.
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