
5/15/2013 · Figure 1: Anatomy of a dopaminergic VTA neuron, illustrating the distal dendritic location from which the axon can originate. Composite confocal images of a VTA neuron recorded in a coronal brain slice of a transgenic mouse expressing green fluorescent protein under the control of the TH gene promoter (TH-GFP+). Monoamines are neurotransmitters that include serotonin,
dopamine, norepinephrine, and epinephrine. Many antidepressant drugs acutely increase synaptic levels of the monoamine neurotransmitter, serotonin, but they may also enhance the levels of two other neurotransmitters, norepinephrine and
dopamine. The observation of this efficacy led to the monoamine hypothesis of depression, which ...
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