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Background: Opioid use disorder during pregnancy is a growing health concern.Methadone maintenance is the treatment of choice but emerging data indicate buprenorphine is a viable alternative. Due to costs and limited accessibility of methadone, pregnant women may require transition from methadone to buprenorphine for maintenance treatment. Take-Overs The Optimism Bias Why Were Wired To Look On The Bright Side Invasion - Issue 1 - Book 1 - The Alien Alliance Spasticity. 5 mg ORALLY 3 times a day; may increase dosage by 15 mg/day increments every 3 days to a MAX dose of 80 mg/day (3 to 4 divided doses) [1] intrathecal test dose, 50 mcg in 1 mL INTRATHECALLY given over at least 1 minute; may increase dosage by 25 mcg increments every 24 hours until a 4- to 8-hour positive clinical response is demonstrated. This book introduces some basic concepts in the addictions field. 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