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Springtime in Babylon Myofibrils are the basic functional unit of skeletal muscle and are composed of syncytia of multinucleated cells that vary considerably in their biochemical and physiological properties. ... the term disc better describes their three-dimensional architecture. During the cardiac cycle, ... Clara Franzini-Armstrong, Andrew G. Engel, ... Functional significance of membrane architecture in skeletal and cardiac muscle / Clara Franzini-Armstrong .doc download download Clara Franzini-Armstrong of University of Pennsylvania, PA (UP). ... Skeletal muscle contractions are initiated by an increase in Ca(2+) released during excitation-contraction (EC) coupling, and ... 8/19/2014 · Ang Guo, a, 1 Xiaoying Zhang, b, 1 Venkat Ramesh Iyer, c, 1 Biyi Chen, a, 1 Caimei Zhang, a William J. Kutschke, a Robert M. Weiss, a Clara Franzini-Armstrong, d, 2 ... et al. Ca2+-dependent proteolysis of junctophilin-1 and junctophilin-2 in skeletal and cardiac muscle. J ... 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The random arrangement of DHPRs in arthropod body muscles indicates that there is no close link ... This matches the architecture of vertebrate cardiac muscle and is in keeping with the similarity in e-c coupling ... 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